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PDBsum entry 2wm0
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protein ligands links
Hydrolase PDB id
2wm0

 

 

 

 

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Contents
Protein chain
538 a.a. *
Ligands
NAG-NAG ×2
NGT
DIO
PEG
Waters ×566
* Residue conservation analysis
PDB id:
2wm0
Name: Hydrolase
Title: Chitinase a from serratia marcescens atcc990 in complex with chitobio- thiazoline thioamide.
Structure: Chitinase a. Chain: a. Fragment: residues 2-520. Synonym: smchi18a. Engineered: yes
Source: Serratia marcescens. Organism_taxid: 615. Atcc: 990. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
1.90Å     R-factor:   0.161     R-free:   0.195
Authors: E.J.Taylor,R.J.Dennis,J.M.Macdonald,C.A.Tarling,S.Knapp,S.G.Withers, G.J.Davies
Key ref: J.M.Macdonald et al. (2010). Chitinase inhibition by chitobiose and chitotriose thiazolines. Angew Chem Int Ed Engl, 49, 2599-2602. PubMed id: 20209544
Date:
29-Jun-09     Release date:   16-Mar-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P07254  (CHIA_SERMA) -  Chitinase A from Serratia marcescens
Seq:
Struc: 		 
Seq:
Struc: 		563 a.a.
538 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 6 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.3.2.1.14  - chitinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Hydrolysis of the 1,4-beta-linkages of N-acetyl-D-glucosamine polymers of chitin.

 

 
Angew Chem Int Ed Engl 49:2599-2602 (2010)
PubMed id: 20209544  
 
 
Chitinase inhibition by chitobiose and chitotriose thiazolines.
J.M.Macdonald, C.A.Tarling, E.J.Taylor, R.J.Dennis, D.S.Myers, S.Knapp, G.J.Davies, S.G.Withers.
 
  ABSTRACT  
 
No abstract given.

 

 

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