PDBsum entry 2w49

Contractile protein

PDB id: 2w49

Contents

Protein chains

159 a.a. *

90 a.a. *

141 a.a. *

277 a.a. *

39 a.a. *

(+ 10 more) 372 a.a. *

Metals

_CA ×16

* Residue conservation analysis

PDB id:

2w49

Name:

Contractile protein

Title:

Isometrically contracting insect asynchronous flight muscle

Structure:

Troponin c, skeletal muscle. Chain: 0, 3, 6, 9. Fragment: residues 5-163. Synonym: tnnc2. Troponin t, fast skeletal muscle isoforms. Chain: 1, 4, 7, y. Fragment: residues 148-237. Synonym: tnnt3. Troponin i, fast skeletal muscle.

Source:

Gallus gallus. Chicken. Organism_taxid: 9031. Tissue: skeletal muscle. Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: skeletal muscle

Authors:

S.Wu,J.Liu,M.C.Reedy,R.T.Tregear,H.Winkler,C.Franzini-Armstrong, H.Sasaki,C.Lucaveche,Y.E.Goldman,M.K.Reedy,K.A.Taylor

Key ref:

S.Wu et al. (2010). Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions. Plos One, 5, 12643. PubMed id: 20844746

Date:

24-Nov-08 Release date: 05-May-10

Protein chains

P02588  (TNNC2_CHICK) -  Troponin C, skeletal muscle from Gallus gallus

Seq: 163 a.a.

Struc: 159 a.a.

Protein chains

P12620  (TNNT3_CHICK) -  Troponin T, fast skeletal muscle isoforms from Gallus gallus

Seq: 263 a.a.

Struc: 90 a.a.

Protein chains

P68246  (TNNI2_CHICK) -  Troponin I, fast skeletal muscle from Gallus gallus

Seq: 183 a.a.

Struc: 141 a.a.*

Protein chains

P58772  (TPM1_RABIT) -  Tropomyosin alpha-1 chain from Oryctolagus cuniculus

Seq: 284 a.a.

Struc: 277 a.a.

Protein chains

P58772  (TPM1_RABIT) -  Tropomyosin alpha-1 chain from Oryctolagus cuniculus

Seq: 284 a.a.

Struc: 39 a.a.

Protein chains

P68135  (ACTS_RABIT) -  Actin, alpha skeletal muscle from Oryctolagus cuniculus

Seq: 377 a.a.

Struc: 372 a.a.

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chains D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S: E.C.3.6.4.- - ?????

Plos One 5:12643 (2010)

PubMed id: 20844746

Electron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions.

S.Wu, J.Liu, M.C.Reedy, R.T.Tregear, H.Winkler, C.Franzini-Armstrong, H.Sasaki, C.Lucaveche, Y.E.Goldman, M.K.Reedy, K.A.Taylor.

ABSTRACT

No abstract given.