 |
PDBsum entry 2vwr
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
|
|
|
|
|
|
|
|
|
Protein binding
|
PDB id
|
|
|
|
2vwr
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
|
* Residue conservation analysis
|
|
|
|
|
PDB id:
|
 |
|
 |
| Name: |
 |
Protein binding
|
 |
|
Title:
|
 |
Crystal structure of the second pdz domain of numb-binding protein 2
|
|
Structure:
|
 |
Ligand of numb protein x 2. Chain: a. Fragment: pdz domain, residues 336-424. Synonym: numb-binding protein 2, pdz domain-containing ring finger protein 1. Engineered: yes. Mutation: yes
|
|
Source:
|
 |
Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
|
|
Resolution:
|
 |
|
1.30Å
|
R-factor:
|
0.136
|
R-free:
|
0.177
|
|
|
Authors:
|
 |
A.K.Roos,K.Guo,N.Burgess-Brown,W.W.Yue,J.M.Elkins,A.C.W.Pike, P.Filippakopoulos,C.H.Arrowsmith,M.Wikstom,A.Edwards,F.Von Delft, C.Bountra,D.Doyle,U.Oppermann
|
|
Key ref:
|
 |
A.K.Roos
et al.
Crystal structure of the second pdz domain of the human numb-Binding protein 2.
To be published,
.
|
 |
|
Date:
|
 |
|
26-Jun-08
|
Release date:
|
16-Sep-08
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
Headers
|
 |
|
|
References
|
|
|
|
|
|
|
Q8N448
(LNX2_HUMAN) -
Ligand of Numb protein X 2 from Homo sapiens
|
|
|
|
Seq: Struc:
|
 |
 |
 |
690 a.a.
95 a.a.*
|
|
|
|
|
|
|
|
|
 |
 |
|
|
Key: |
 |
PfamA domain |
 |
 |
 |
Secondary structure |
 |
 |
CATH domain |
 |
|
*
PDB and UniProt seqs differ
at 7 residue positions (black
crosses)
|
|
|
|
|
');
}
}
 |