UniProt functional annotation for P0A7M6

UniProt code: P0A7M6.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Function: Binds 23S rRNA. It is not essential for growth.
Function: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. Contacts trigger factor (PubMed:12226666). {ECO:0000269|PubMed:12226666}.
Subunit: Part of the 50s ribosomal subunit. Contacts protein L23 (PubMed:2665813), trigger factor (PubMed:12226666) and protein nascent chains (PubMed:12756233). Might also contact SecE and probably does contact SecG when the SecYEG translocation complex is docked with the ribosome. {ECO:0000269|PubMed:12226666, ECO:0000269|PubMed:12756233, ECO:0000269|PubMed:2665813}.
Mass spectrometry: Mass=7273.4; Method=MALDI; Range=1-63; Evidence={ECO:0000269|PubMed:10094780};
Disruption phenotype: Cells missing both S17 and L29 grow very slowly and have a rather unstable temperature-sensitive phenotype. {ECO:0000269|PubMed:12226666}.
Similarity: Belongs to the ribosomal protein L29P family. {ECO:0000305}.
Sequence caution: Sequence=Ref.1; Type=Miscellaneous discrepancy; Note=Exchange of two tryptic peptides.; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.