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UniProt functional annotation for Q9Y3Y4 | ||
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| UniProt code: Q9Y3Y4. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Involved in signal transduction through the Wnt pathway. |
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| Subunit: | |
Interacts with BCL9 via The PHD-type zinc finger motiv, and thereby becomes part of the nuclear beta-catenin/TCF complex. Identified in a complex with BCL9L, CDC73, CTNNB1 and PYGO1. Interacts with histone H3 mono-, di- or tri-methylated at 'Lys4' (H3K4me1, H3K4me2, H3K4me3); the interaction is enhanced by the interaction with BCL9. {ECO:0000269|PubMed:17113272, ECO:0000269|PubMed:18498752}. |
| Subcellular location: | |
Nucleus {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.