UniProt functional annotation for P00698

UniProt code: P00698.

Organism: Gallus gallus (Chicken).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus.
Function: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte- macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus. {ECO:0000255|PROSITE- ProRule:PRU00680, ECO:0000269|PubMed:22044478}.
Catalytic activity: Hydrolysis of (1->4)-beta-linkages between N- acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
Subunit: Monomer.
Subcellular location: Secreted.
Tissue specificity: In the egg white and polymorphonuclear leukocytes.
Allergen: Causes an allergic reaction in human.
Miscellaneous: Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.
Similarity: Belongs to the glycosyl hydrolase 22 family. {ECO:0000255|PROSITE-ProRule:PRU00680}.

Annotations taken from UniProtKB at the EBI.