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UniProt functional annotation for P56282 | ||
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| UniProt code: P56282. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity). {ECO:0000250|UniProtKB:P24482, ECO:0000269|PubMed:10801849}. |
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| Subunit: | |
Component of the DNA polymerase epsilon complex consisting of four subunits: the catalytic subunit POLE and the accessory subunits POLE2, POLE3 and POLE4. {ECO:0000269|PubMed:10801849}. |
| Subcellular location: | |
Nucleus. |
| Miscellaneous: | |
In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis. |
| Similarity: | |
Belongs to the DNA polymerase epsilon subunit B family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.