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PDBsum entry 2tun

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protein Protein-protein interface(s) links
Lymphokine PDB id
2tun
Jmol
Contents
Protein chains
(+ 0 more) 151 a.a. *
* Residue conservation analysis
PDB id:
2tun
Name: Lymphokine
Title: Conformational changes in the (ala-84-val) mutant of tumor n factor
Structure: Tumor necrosis factor-alpha. Chain: a, b, c, d, e, f. Engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606
Biol. unit: Hexamer (from PQS)
Resolution:
3.10Å     R-factor:   0.198    
Authors: P.Saludjian,T.Prange
Key ref: P.Saludjian et al. Conformational changes in the (ala-84-Val) mutant of tumor necrosis factor. To be published, .
Date:
06-Oct-93     Release date:   31-Jan-94    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01375  (TNFA_HUMAN) -  Tumor necrosis factor
Seq:
Struc:
233 a.a.
151 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     membrane   1 term 
  Biological process     immune response   1 term 
  Biochemical function     tumor necrosis factor receptor binding     1 term