UniProt functional annotation for P29768

UniProt code: P29768.

Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Function: Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections.
Catalytic activity: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
Subunit: Monomer.
Similarity: Belongs to the glycosyl hydrolase 33 family. {ECO:0000305}.
Similarity: Contains 4 BNR repeats. {ECO:0000305}.
Sequence caution: Sequence=AAL19864.1; Type=Erroneous initiation; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.