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UniProt functional annotation for Q8TE68 | ||
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| UniProt code: Q8TE68. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. {ECO:0000269|PubMed:14565974}. |
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| Subunit: | |
Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin. {ECO:0000269|PubMed:14565974}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:14565974}. |
| Tissue specificity: | |
Detected in placenta. {ECO:0000269|PubMed:14565974}. |
| Similarity: | |
Belongs to the EPS8 family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=AAG03038.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=AAG03039.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.