PDBsum entry 2rna

Transferase

PDB id: 2rna

Contents

Protein chain

64 a.a. *

* Residue conservation analysis

PDB id:

2rna

Name:

Transferase

Title:

Itk sh3 average minimized

Structure:

Tyrosine-protein kinase itk/tsk. Chain: a. Fragment: sh3 domain. Synonym: t-cell-specific kinase, il-2-inducible t-cell kinase, kinase emt, kinase tlk. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: itk, emt, tlk, tsk. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

NMR struc:

1 models

Authors:

A.J.Severin

Key ref:

A.J.Severin et al. Nmr structure note: murine itk sh3 domain. To be published, .

Date:

08-Dec-07 Release date: 25-Dec-07

Protein chain

Q03526  (ITK_MOUSE) -  Tyrosine-protein kinase ITK/TSK from Mus musculus

Seq: 625 a.a.

Struc: 64 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.2 - non-specific protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site