Gene Ontology (GO) functional annotation for PDB entry 2rk3

GO functional annotation for 2rk3

  Cellular component Chain(s)
  0016020  
  membrane
  0005886  
    plasma membrane
  0005737  
  cytoplasm
  0045121  
      membrane raft
  0070062  
    extracellular vesicular exosome
  0005634  
    nucleus
  0005739  
    mitochondrion
  0005829  
    cytosol
  0000785  
          chromatin
  0016605  
            PML body
  0005747  
  ?
 
  Biological process Chain(s)
  0006950  
  response to stress
  0008219  
  cell death
  0007005  
    mitochondrion organization
  0007338  
    single fertilization
  0008344  
    adult locomotory behavior
  0006914  
      autophagy
  0006954  
      inflammatory response
  0034599  
    cellular response to oxidative stress
  0032091  
        negative regulation of protein binding
  0034614  
        cellular response to reactive oxygen species
  0010629  
        negative regulation of gene expression
  0032757  
        positive regulation of interleukin-8 production
  0006508  
  proteolysis
  0019243  
        methylglyoxal catabolic process to D-lactate
  0019249  
        lactate biosynthetic process
  0001963  
          synaptic transmission, dopaminergic
  0001933  
            negative regulation of protein phosphorylation
  0031397  
            negative regulation of protein ubiquitination
  0033234  
            negative regulation of protein sumoylation
  0006469  
            negative regulation of protein kinase activity
  0036471  
  ?
  0060765  
              regulation of androgen receptor signaling pathway
  0090073  
              positive regulation of protein homodimerization activity
  1900182  
              positive regulation of protein localization to nucleus
  0055114  
  oxidation-reduction process
  0042743  
                  hydrogen peroxide metabolic process
  0060548  
                  negative regulation of cell death
  0050727  
                  regulation of inflammatory response
  0042542  
                    response to hydrogen peroxide
  0046295  
                    glycolate biosynthetic process
  0043066  
        negative regulation of apoptotic process
  0051444  
                      negative regulation of ubiquitin-protein ligase activity
  0070301  
          cellular response to hydrogen peroxide
  0043523  
          regulation of neuron apoptotic process
  0050821  
          protein stabilization
  0043524  
          negative regulation of neuron apoptotic process
  0051881  
                        regulation of mitochondrial membrane potential
  0051899  
                        membrane depolarization
  0060081  
                        membrane hyperpolarization
  0046826  
                        negative regulation of protein export from nucleus
  0051583  
                        dopamine uptake involved in synaptic transmission
  0045944  
              positive regulation of transcription from RNA polymerase II promoter
  1901215  
  ?
  1901671  
  ?
  1901984  
  ?
  1902958  
  ?
  1903073  
  ?
  1903094  
  ?
  1903122  
  ?
  1903168  
  ?
  1903178  
  ?
  1903181  
  ?
  1903190  
  ?
  1903197  
  ?
  1903200  
  ?
  1903202  
  ?
  1903206  
  ?
  1903208  
  ?
  1903377  
  ?
  2000157  
                            negative regulation of ubiquitin-specific protease activity
  2000277  
  ?
 
  2000825  
  ?
 
  2001237  
  ?
 
  2001268  
  ?
 
  0045560  
  ?
 
  Biochemical function Chain(s)
  0005515  
  protein binding
  0016787  
  hydrolase activity
  0019172  
  glyoxalase III activity
  0003723  
    RNA binding
  0004601  
    peroxidase activity
  0005102  
    receptor binding
  0008134  
    transcription factor binding
  0008233  
    peptidase activity
  0016684  
    oxidoreductase activity, acting on peroxide as acceptor
  0019899  
    enzyme binding
  0019955  
    cytokine binding
  0003713  
    transcription coactivator activity
  0003729  
      mRNA binding
  0016532  
        superoxide dismutase copper chaperone activity
  0036470  
  ?
  0036478  
  ?
  0044388  
          small protein activating enzyme binding
  0044390  
          small protein conjugating enzyme binding
  0097110  
          scaffold protein binding
  0042802  
    identical protein binding
  0070491  
            repressing transcription factor binding
  0042803  
      protein homodimerization activity
  0051920  
              peroxiredoxin activity
  0050681  
                androgen receptor binding
  1903135  
  ?
  1903136  
  ?
  1990381  
  ?
  1990422  
  ?
  0001047  
  ?
 
  0003690  
  ?
 
  0003697  
  ?