PDBsum entry 2rey

Gene regulation

PDB id: 2rey

Contents

Protein chain

91 a.a. *

Waters ×42

* Residue conservation analysis

PDB id:

2rey

Name:

Gene regulation

Title:

Crystal structure of the pdz domain of human dishevelled 2 (homologous to drosophila dsh)

Structure:

Segment polarity protein dishevelled homolog dvl-2. Chain: a. Fragment: pdz domain: residues 261-355. Synonym: dishevelled-2, dsh homolog 2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: dvl2. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.55Å R-factor: 0.212 R-free: 0.240

Authors:

E.Papagrigoriou,C.Gileadi,J.Elkins,C.Cooper,E.Ugochukwu,A.Turnbull, A.C.W.Pike,O.Gileadi,F.Von Delft,M.Sundstrom,C.H.Arrowsmith, J.Weigelt,A.M.Edwards,D.Doyle,Structural Genomics Consortium (Sgc)

Key ref:

E.Papagrigoriou et al. Crystal structure of the pdz domains of human dishevelled 2 (homologous to drosophila dsh).. To be published, .

Date:

27-Sep-07 Release date: 23-Oct-07

Protein chain

O14641  (DVL2_HUMAN) -  Segment polarity protein dishevelled homolog DVL-2 from Homo sapiens

Seq: 736 a.a.

Struc: 91 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)