PDBsum entry 2r4h

Transferase

PDB id: 2r4h

Contents

Protein chains

90 a.a. *

98 a.a. *

Ligands

HIS-HIS

HIS-HIS-HIS

Waters ×114

* Residue conservation analysis

PDB id:

2r4h

Name:

Transferase

Title:

Crystal structure of a c1190s mutant of the 6th pdz domain of human membrane associated guanylate kinase

Structure:

Membrane-associated guanylate kinase, ww and pdz domain- containing protein 1. Chain: a, b, c. Fragment: 6th pdz domain: residues 1149-1233. Synonym: bai1-associated protein 1, bap-1, membrane-associated guanylate kinase inverted 1, magi-1, atrophin-1-interacting protein 3, aip3, ww domain-containing protein 3, wwp3, trinucleotide repeat- containing gene 19 protein. Engineered: yes.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Tissue: brain. Gene: magi1, baiap1, bap1, tnrc19. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.05Å R-factor: 0.191 R-free: 0.258

Authors:

E.Ugochukwu,E.S.Pilka,V.Hozjan,K.L.Kavanagh,C.Cooper,A.C.W.Pike, J.M.Elkins,D.A.Doyle,F.Von Delft,M.Sundstrom,C.H.Arrowsmith, J.Weigelt,A.M.Edwards,U.Oppermann,Structural Genomics Consortium (Sgc)

Key ref:

E.Ugochukwu et al. Crystal structure of a c1190s mutant of the 6th pdz domain of human membrane associated guanylate kinase.. To be published, .

Date:

31-Aug-07 Release date: 16-Oct-07

Protein chains

Q96QZ7  (MAGI1_HUMAN) -  Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 from Homo sapiens

Seq: 1491 a.a.

Struc: 90 a.a.*

Protein chain

Q96QZ7  (MAGI1_HUMAN) -  Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 from Homo sapiens

Seq: 1491 a.a.

Struc: 98 a.a.*

* PDB and UniProt seqs differ at 15 residue positions (black crosses)