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UniProt functional annotation for Q6GFF9 | ||
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| UniProt code: Q6GFF9. |
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| Organism: | |
Staphylococcus aureus (strain MRSA252). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. |
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| Function: | |
Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. {ECO:0000269|PubMed:17535816}. |
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| Catalytic activity: | |
Reaction=a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3- phosphate + ADP + H(+); Xref=Rhea:RHEA:10272, ChEBI:CHEBI:15378, ChEBI:CHEBI:17815, ChEBI:CHEBI:30616, ChEBI:CHEBI:58608, ChEBI:CHEBI:456216; EC=2.7.1.107; Evidence={ECO:0000269|PubMed:18611377}; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:18611377}; Note=Binds 1 Mg(2+) ion per subunit. This ion appears to have a structural role and is required for catalytic activity. {ECO:0000269|PubMed:18611377}; |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:18611377}. |
| Similarity: | |
Belongs to the diacylglycerol/lipid kinase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.