UniProt functional annotation for P21980

UniProt code: P21980.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
 
Catalytic activity: Protein glutamine + alkylamine = protein N(5)- alkylglutamine + NH(3). {ECO:0000255|PROSITE-ProRule:PRU10024}.
Cofactor: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000250};
Subunit: Monomer.
Induction: By retinoic acid.
Similarity: Belongs to the transglutaminase superfamily. Transglutaminase family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.