UniProt functional annotation for O34627



	UniProt functional annotation for O34627

UniProt code: O34627.

Organism: Bacillus subtilis (strain 168).

Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.

Function: Exhibits the same spectroscopical features and blue-light induced photochemistry as plants phototropins, with the reversible formation of a blue-shifted photoproduct, assigned to an FMN-cysteine thiol adduct. Although it is a positive regulator in the activation of the environmental signaling branch of the general stress transcription factor sigma-B, its precise role is undetermined. {ECO:0000269|PubMed:11157946}.

Subunit: Homodimer. {ECO:0000269|PubMed:17764689}.

Ptm: FMN binds covalently to cysteine after exposure to blue light and this bond is spontaneously broken in the dark.

Disruption phenotype: Cells lacking this gene have a twofold decreased response to salt and ethanol stress, and a somewhat reduced response to energy stress, indicating that PhoT is a positive regulator of sigma-B activity. It acts independently of both RsbRA and RsbRB (YkoB). {ECO:0000269|PubMed:11157946}.

Annotations taken from UniProtKB at the EBI.


Organism:		Bacillus subtilis (strain 168).
Taxonomy:		Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.



Function:		Exhibits the same spectroscopical features and blue-light induced photochemistry as plants phototropins, with the reversible formation of a blue-shifted photoproduct, assigned to an FMN-cysteine thiol adduct. Although it is a positive regulator in the activation of the environmental signaling branch of the general stress transcription factor sigma-B, its precise role is undetermined. {ECO:0000269\|PubMed:11157946}.


Subunit:		Homodimer. {ECO:0000269\|PubMed:17764689}.
Ptm:		FMN binds covalently to cysteine after exposure to blue light and this bond is spontaneously broken in the dark.
Disruption phenotype:		Cells lacking this gene have a twofold decreased response to salt and ethanol stress, and a somewhat reduced response to energy stress, indicating that PhoT is a positive regulator of sigma-B activity. It acts independently of both RsbRA and RsbRB (YkoB). {ECO:0000269\|PubMed:11157946}.