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UniProt functional annotation for Q9UL52 | ||
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| UniProt code: Q9UL52. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. {ECO:0000250|UniProtKB:Q5S248}. |
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| Activity regulation: | |
Inhibited by SERPINA5. {ECO:0000269|PubMed:14696115}. |
| Subunit: | |
Forms a heterodimer with SERPINA5 and SERPINE1. |
| Subcellular location: | |
Cell membrane {ECO:0000250|UniProtKB:Q5S248}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q5S248}. |
| Subcellular location: | |
[Transmembrane protease serine 11E catalytic chain]: Secreted {ECO:0000250|UniProtKB:Q5S248}. Note=Activated by cleavage and secreted. {ECO:0000250|UniProtKB:Q5S248}. |
| Tissue specificity: | |
Expression can only be detected in tissues derived from the head and neck, and in skin, prostate and testis. {ECO:0000269|PubMed:11161383}. |
| Ptm: | |
N-glycosylated. {ECO:0000250}. |
| Similarity: | |
Belongs to the peptidase S1 family. {ECO:0000255|PROSITE- ProRule:PRU00274}. |
Annotations taken from UniProtKB at the EBI.