UniProt functional annotation for Q9WZF8

UniProt code: Q9WZF8.

Organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099).
Taxonomy: Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
Function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). {ECO:0000250}.
Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
Subcellular location: Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm. {ECO:0000250}.
Domain: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own. {ECO:0000250}.
Similarity: Belongs to the FKBP-type PPIase family. Tig subfamily. {ECO:0000305}.
Similarity: Contains 1 PPIase FKBP-type domain. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.