PDBsum entry 2nct

Viral protein

PDB id: 2nct

Contents

Protein chain

36 a.a.

PDB id:

2nct

Name:

Viral protein

Title:

Nmr assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol

Structure:

Envelope glycoprotein gp41. Chain: a. Fragment: unp residues 95-121. Engineered: yes

Source:

Synthetic: yes. Human immunodeficiency virus 1. Organism_taxid: 11676

NMR struc:

20 models

Authors:

M.Jimenez,J.L.Nieva,E.Rujas,A.Partida-Hanon,M.Bruix

Key ref:

E.Rujas et al. (2016). Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface. Sci Rep, 6, 38177. PubMed id: 27905530 DOI: 10.1038/srep38177

Date:

14-Apr-16 Release date: 22-Feb-17

Protein chain

Q66X49  (Q66X49_9HIV1) -  Env polyprotein (Fragment) from Human immunodeficiency virus 1

Seq: 133 a.a.

Struc: 36 a.a.*

* PDB and UniProt seqs differ at 9 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?

DOI no: 10.1038/srep38177

Sci Rep 6:38177 (2016)

PubMed id: 27905530

Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.

E.Rujas, J.M.Caaveiro, A.Partida-Hanon, N.Gulzar, K.Morante, B.Apellániz, M.García-Porras, M.Bruix, K.Tsumoto, J.K.Scott, M.�.�.Jiménez, J.L.Nieva.

ABSTRACT

No abstract given.