PDBsum entry 2n7k

Signaling protein

PDB id: 2n7k

Contents

Protein chains

76 a.a.

52 a.a.

PDB id:

2n7k

Name:

Signaling protein

Title:

Unveiling the structural determinants of kiaa0323 binding preference for nedd8

Structure:

Nedd8. Chain: a. Synonym: neddylin, neural precursor cell expressed developmentally down-regulated protein 8, nedd-8, ubiquitin-like protein nedd8. Engineered: yes. Protein khnyn. Chain: b. Fragment: residues 627-678. Synonym: kh and nyn domain-containing protein.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: nedd8. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: khnyn, kiaa0323.

NMR struc:

11 models

Authors:

E.Santonico,R.Nepravishta,A.Mattioni,E.Valentini,W.Mandaliti, R.Procopio,M.Iannuccelli,L.Castagnoli,S.Polo,M.Paci,G.Cesareni

Key ref:

E.Santonico et al. Unveiling the structural determinants of kiaa0323 bin preference for nedd8. To be published, .

Date:

14-Sep-15 Release date: 14-Sep-16

Protein chain

Q15843  (NEDD8_HUMAN) -  NEDD8 from Homo sapiens

Seq: 81 a.a.

Struc: 76 a.a.

Protein chain

O15037  (KHNYN_HUMAN) -  Protein KHNYN from Homo sapiens

Seq: 678 a.a.

Struc: 52 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?