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PDBsum entry 2mwc
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Structural protein
PDB id
2mwc
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Contents
Protein chain
102 a.a.
PDB id:
2mwc
Links
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RCSB
MMDB
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Proteopedia
CATH
SCOP
PDBSWS
ProSAT
Name:
Structural protein
Title:
Solution structure of human obscurin ig58
Structure:
Obscurin. Chain: a. Fragment: unp residues 4337-4429. Synonym: obscurin-rhogef, obscurin-myosin light chain kinase, obscurin-mlck. Engineered: yes
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: obscn, kiaa1556, kiaa1639. Expressed in: escherichia coli. Expression_system_taxid: 562.
NMR struc:
20 models
Authors:
N.T.Wright,L.C.Meyer
Key ref:
N.T.Wright et al. Obscurin ig58-Ig59 causes malformed muscle structure.
To be published
, .
Date:
03-Nov-14
Release date:
09-Dec-15
PROCHECK
Headers
References
Protein chain
Q5VST9
(OBSCN_HUMAN) - Obscurin from Homo sapiens
Seq:
Struc:
 
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Seq:
Struc:
7968 a.a.
102 a.a.
*
Key:
Secondary structure
CATH domain
*
PDB and UniProt seqs differ at 10 residue positions (black crosses)
Enzyme reactions
Enzyme class:
E.C.2.7.11.1
- non-specific serine/threonine protein kinase.
[IntEnz]
[ExPASy]
[KEGG]
[BRENDA]
Reaction:
1.
L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H
+
2.
L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H
+
L-seryl-[protein]
+
ATP
=
O-phospho-L-seryl-[protein]
+
ADP
+
H(+)
L-threonyl-[protein]
+
ATP
=
O-phospho-L-threonyl-[protein]
+
ADP
+
H(+)
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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