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UniProt functional annotation for P46109 | ||
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| UniProt code: P46109. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
May mediate the transduction of intracellular signals. |
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| Subunit: | |
Interacts with tyrosine-phosphorylated EPOR and INPP5D/SHIP1 (PubMed:11443118). Interacts with DOCK2 and DOCK5 via its first SH3 domain (PubMed:12393632, PubMed:19004829). Interacts with phosphorylated CBLB and IRS4 (PubMed:10022120, PubMed:9614078). {ECO:0000269|PubMed:10022120, ECO:0000269|PubMed:11443118, ECO:0000269|PubMed:12393632, ECO:0000269|PubMed:19004829, ECO:0000269|PubMed:9614078}. |
| Similarity: | |
Belongs to the CRK family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.