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PDBsum entry 2lfg
Go to PDB code:
Hormone receptor
PDB id
2lfg
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Contents
Protein chain
113 a.a.
PDB id:
2lfg
Links
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RCSB
MMDB
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Proteopedia
CATH
SCOP
PDBSWS
ProSAT
Name:
Hormone receptor
Title:
Solution structure of the human prolactin receptor ecd domain d2
Structure:
Prolactin receptor. Chain: a. Fragment: fibronectin type-iii 2 domain residues 99-210. Synonym: prl-r. Engineered: yes
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: prlr. Expressed in: escherichia coli. Expression_system_taxid: 469008.
NMR struc:
20 models
Authors:
R.Dagil,M.J.Knudsen,B.B.Kragelund,C.O'Shea,K.Teilum
Key ref:
R.Dagil et al. (2012). The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor.
Structure
,
20
, 270-282.
PubMed id:
22325776
Date:
30-Jun-11
Release date:
15-Feb-12
PROCHECK
Headers
References
Protein chain
?
P16471
(PRLR_HUMAN) - Prolactin receptor from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
622 a.a.
113 a.a.
*
Key:
PfamA domain
Secondary structure
CATH domain
*
PDB and UniProt seqs differ at 1 residue position (black cross)
Enzyme reactions
Enzyme class:
E.C.?
[IntEnz]
[ExPASy]
[KEGG]
[BRENDA]
Structure
20
:270-282 (2012)
PubMed id:
22325776
The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor.
R.Dagil,
M.J.Knudsen,
J.G.Olsen,
C.O'Shea,
M.Franzmann,
V.Goffin,
K.Teilum,
J.Breinholt,
B.B.Kragelund.
ABSTRACT
No abstract given.
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