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PDBsum entry 2lfg

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protein links
Hormone receptor PDB id
2lfg

 

 

 

 

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Contents
Protein chain
113 a.a.
PDB id:
2lfg
Name: Hormone receptor
Title: Solution structure of the human prolactin receptor ecd domain d2
Structure: Prolactin receptor. Chain: a. Fragment: fibronectin type-iii 2 domain residues 99-210. Synonym: prl-r. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: prlr. Expressed in: escherichia coli. Expression_system_taxid: 469008.
NMR struc: 20 models
Authors: R.Dagil,M.J.Knudsen,B.B.Kragelund,C.O'Shea,K.Teilum
Key ref: R.Dagil et al. (2012). The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor. Structure, 20, 270-282. PubMed id: 22325776
Date:
30-Jun-11     Release date:   15-Feb-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P16471  (PRLR_HUMAN) -  Prolactin receptor from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
622 a.a.
113 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Structure 20:270-282 (2012)
PubMed id: 22325776  
 
 
The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor.
R.Dagil, M.J.Knudsen, J.G.Olsen, C.O'Shea, M.Franzmann, V.Goffin, K.Teilum, J.Breinholt, B.B.Kragelund.
 
  ABSTRACT  
 
No abstract given.

 

 

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