PDBsum entry 2l6k

Protein binding

PDB id: 2l6k

Contents

Protein chain

115 a.a.

PDB id:

2l6k

Name:

Protein binding

Title:

Solution structure of a nonphosphorylated peptide recognizing domain

Structure:

Tensin-like c1 domain-containing phosphatase. Chain: a. Fragment: nonphosphorylated peptide recognizing domain, sh2 domain, unp residues 2-115. Synonym: c1 domain-containing phosphatase and tensin homolog, c1-ten, tensin-2. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.

NMR struc:

20 models

Authors:

K.Dai,S.Liao,J.Zhang,X.Zhang,X.Tu

Key ref:

K.Dai et al. (2011). Solution structure of tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1. Plos One, 6, e21965. PubMed id: 21765928

Date:

22-Nov-10 Release date: 12-Oct-11

Protein chain

Q63HR2  (TNS2_HUMAN) -  Tensin-2 from Homo sapiens

Seq: 1409 a.a.

Struc: 115 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.1.3.48 - protein-tyrosine-phosphatase.
• Reaction: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

Key reference

Plos One 6:e21965 (2011)

PubMed id: 21765928

Solution structure of tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1.

K.Dai, S.Liao, J.Zhang, X.Zhang, X.Tu.

ABSTRACT

No abstract given.