PDBsum entry 2l53

Ca-binding protein/proton transport

PDB id: 2l53

Contents

Protein chains

148 a.a. *

31 a.a. *

* Residue conservation analysis

PDB id:

2l53

Name:

Ca-binding protein/proton transport

Title:

Solution nmr structure of apo-calmodulin in complex with the iq motif of human cardiac sodium channel nav1.5

Structure:

Calmodulin. Chain: a. Fragment: calmodulin. Synonym: cam. Engineered: yes. Voltage-gated sodium channel type v alpha isoform b variant. Chain: b. Fragment: human cardiac sodium channel nav1.5 iq motif.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: calm1, calm, cam, cam1, calm2, cam2, camb, calm3, calml2, cam3, camc, camiii. Expressed in: escherichia coli. Expression_system_taxid: 562.

NMR struc:

20 models

Authors:

B.Chagot,W.J.Chazin

Key ref:

B.Chagot and W.J.Chazin (2011). Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5. J Mol Biol, 406, 106-119. PubMed id: 21167176

Date:

24-Oct-10 Release date: 05-Jan-11

Protein chain

No UniProt id for this chain

Struc: 148 a.a.

Protein chain

Q14524  (SCN5A_HUMAN) -  Sodium channel protein type 5 subunit alpha from Homo sapiens

Seq: 2016 a.a.

Struc: 31 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain B: E.C.?

J Mol Biol 406:106-119 (2011)

PubMed id: 21167176

Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5.

B.Chagot, W.J.Chazin.

ABSTRACT

No abstract given.