PDBsum entry 2l3s

Structural protein

PDB id

2l3s

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Contents

			Protein chain

					163 a.a. *

* Residue conservation analysis

PDB id:

2l3s

Links
- PDBe
- RCSB
- MMDB
- JenaLib
- Proteopedia
- CATH
- SCOP
- PDBSWS
- ProSAT

Name:

Structural protein

Title:

Structure of the autoinhibited crk

Structure:

Autoinhibited crk protein. Chain: a. Synonym: proto-oncogenE C-crk, p38. Engineered: yes

Source:

Gallus gallus. Bantam,chickens. Organism_taxid: 9031. Gene: crk. Expressed in: escherichia coli. Expression_system_taxid: 562.

NMR struc:

20 models

Authors:

C.G.Kalodimos,P.Sarkar,T.Saleh,S.R.Tzeng,R.Birge

Key ref:

P.Sarkar et al. (2011). Structural basis for regulation of the Crk signaling protein by a proline switch. Nat Chem Biol, 7, 51-57. PubMed id: 21131971

Date:

21-Sep-10

Release date:

08-Dec-10

PROCHECK

	Headers

	References

Protein chain

Q04929 (CRK_CHICK) - Adapter molecule crk from Gallus gallus

Seq: Struc:					305 a.a. 163 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.?

[IntEnz] [ExPASy] [KEGG] [BRENDA]

	Nat Chem Biol 7:51-57 (2011)
PubMed id: 21131971

Structural basis for regulation of the Crk signaling protein by a proline switch.
P.Sarkar, T.Saleh, S.R.Tzeng, R.B.Birge, C.G.Kalodimos.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

21404360

C.G.Kalodimos (2011).
NMR reveals novel mechanisms of protein activity regulation.

Protein Sci, 20, 773-782.

21164511

L.K.Nicholson, and S.De (2011).
Structural biology: The twist in Crk signaling revealed.

Nat Chem Biol, 7, 5-6.

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.