PDBsum entry 2l0t

Protein transport

PDB id: 2l0t

Contents

Protein chains

76 a.a. *

163 a.a. *

* Residue conservation analysis

PDB id:

2l0t

Name:

Protein transport

Title:

Solution structure of the complex of ubiquitin and the vhs domain of stam2

Structure:

Ubiquitin. Chain: a. Engineered: yes. Signal transducing adapter molecule 2. Chain: b. Fragment: vhs domain (unp residues 1-150). Synonym: stam-2, hrs-binding protein. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: stam2, hbp.

NMR struc:

10 models

Authors:

A.Lange,D.Hoeller,H.Wienk,O.Marcillat,J.Lancelin,O.Walker

Key ref:

A.Lange et al. (2011). NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin. Biochemistry, 50, 48-62. PubMed id: 21121635

Date:

15-Jul-10 Release date: 15-Dec-10

Protein chain

P62979  (RS27A_HUMAN) -  Ubiquitin-ribosomal protein eS31 fusion protein from Homo sapiens

Seq: 156 a.a.

Struc: 76 a.a.

Protein chain

O75886  (STAM2_HUMAN) -  Signal transducing adapter molecule 2 from Homo sapiens

Seq: 525 a.a.

Struc: 163 a.a.*

* PDB and UniProt seqs differ at 6 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?

Biochemistry 50:48-62 (2011)

PubMed id: 21121635

NMR reveals a different mode of binding of the Stam2 VHS domain to ubiquitin and diubiquitin.

A.Lange, D.Hoeller, H.Wienk, O.Marcillat, J.M.Lancelin, O.Walker.

ABSTRACT

No abstract given.