 |
PDBsum entry 2l0b
|
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
|
|
* Residue conservation analysis
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Ligase
|
|
|
Title:
|
|
Solution nmr structure of zinc finger domain of e3 ubiquitin-protein ligase praja-1 from homo sapiens, northeast structural genomics consortium (nesg) target hr4710b
|
|
Structure:
|
|
E3 ubiquitin-protein ligase praja-1. Chain: a. Fragment: ring-type zinc finger residues 564-643. Synonym: praja1, ring finger protein 70. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: pja1, rnf70. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
NMR struc:
|
|
20 models
|
|
|
Authors:
|
|
G.Liu,S.Tong,K.Hamilton,C.Ciccosanti,R.Shastry,T.B.Acton,R.Xiao, J.K.Everett,G.T.Montelione,Northeast Structural Genomics Consortium (Nesg)
|
|
Key ref:
|
|
G.Liu
et al.
Solution structure of zinc finger domain of e3 ubiquitin-Protein ligase protein praja-1 from homo sa northeast structural genomics consortium (nesg) targe hr4710b.
To be published,
.
|
|
|
Date:
|
|
|
30-Jun-10
|
Release date:
|
25-Aug-10
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q8NG27
(PJA1_HUMAN) -
E3 ubiquitin-protein ligase Praja-1 from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
643 a.a.
91 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 12 residue positions (black
crosses)
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class:
|
|
E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
|
|
|
|
|
|
|
Reaction:
|
|
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
|
|
|
|
|
|
|
|
Links
