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UniProt functional annotation for P13127 | ||
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| UniProt code: P13127. |
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| Organism: | |
Gallus gallus (Chicken). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus. |
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| Function: | |
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. {ECO:0000250|UniProtKB:P52907}. |
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| Subunit: | |
Heterodimer of an alpha and a beta subunit. Component of the WASH complex (By similarity). {ECO:0000250|UniProtKB:P52907}. |
| Subcellular location: | |
Cytoplasm, myofibril, sarcomere, Z line. Note=CapZ is located at the Z line in chicken muscle. |
| Tissue specificity: | |
Present in all tissues examined. |
| Similarity: | |
Belongs to the F-actin-capping protein alpha subunit family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.