UniProt functional annotation for P0ADY1

UniProt code: P0ADY1.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
 
Function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins. Its preference at the P1 position of the peptide substrate is Glu > Leu > Ala > His > Val > Phe > Ile > Gly > Lys > Thr.
 
Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
Subunit: Has been isolated as a homodimer and homotrimer from inner membrane preparations.
Subcellular location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Induction: By heat shock.
Similarity: Contains 1 PpiC domain.

Annotations taken from UniProtKB at the EBI.