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UniProt functional annotation for Q12432 | ||
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| UniProt code: Q12432. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. {ECO:0000269|PubMed:11036083, ECO:0000269|PubMed:14701747, ECO:0000269|PubMed:15045029}. |
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| Subunit: | |
Component of the NuA4 histone acetyltransferase complex composed of at least ACT1, ARP4, YAF9, VID21, SWC4, EAF3, EAF5, EAF6, EAF7, EPL1, ESA1, TRA1 and YNG2. {ECO:0000269|PubMed:11036083, ECO:0000269|PubMed:15045029, ECO:0000269|PubMed:15353583, ECO:0000269|PubMed:15485911}. |
| Subcellular location: | |
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00972, ECO:0000269|PubMed:14562095}. |
| Miscellaneous: | |
Present with 1890 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the MRG family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.