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PDBsum entry 2iul

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Protein chain A PDB id
2iul
Protein chain A highlighted
(click to view)
 
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
3 sheets
2 beta hairpins
1 beta bulge
6 strands
31 helices
63 helix-helix interacs
30 beta turns
5 gamma turns
3 disulphides
Catalytic residues
E411-Y523
A354-E384-H353-H513-Y523
Active sites
AC1
AC2
AC4
AC5
AC6
AC7
AC8
AC9
BC1
BC2
Variants
Ile193Val
His410Gln
Thr311Met
Thr605Met
Asn431Lys
Pro497Thr
Met223Thr
Thr582Met
  
Residue conservation: Chain (583 residues)

UniProt code: P12821   [Pfam]

Sequence coloured by residue conservation:

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
Disulphides:   
    disulphide bond
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand     to metal
PDB SITE records:   
 AC1  AC2  AC3  AC4  AC5
 AC6  AC7  AC8  AC9  BC1
 BC2
PROSITE patterns:   
Low   High conservation
Conservation colouring:     Low 1 2 3 4 5 6 7 8 9 High
View:
Protein surface showing most poorly (1) and highly conserved (7 8 9) regions
ConSurf representation of conserved regions: 1 2 3 4 5 6 7 8 9
Download tab-separated text file of ConSurf analysis
Generate Raster3D image of surface coloured by conservation
ConSurf-DB ConSurf-DB data (including mult seq alignment) for 2iul, chain A
Residue conservation calculated by ConSurf-DB.
  
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