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UniProt functional annotation for Q45458 | ||
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| UniProt code: Q45458. |
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| Organism: | |
Geobacillus stearothermophilus (Bacillus stearothermophilus). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus. |
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| Function: | |
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. {ECO:0000256|RuleBase:RU004460}. |
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| Catalytic activity: | |
Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7; Evidence={ECO:0000256|ARBA:ARBA00001680, ECO:0000256|RuleBase:RU004460}; |
| Subunit: | |
Single-chain monomer with multiple functions. {ECO:0000256|ARBA:ARBA00011541, ECO:0000256|RuleBase:RU004460}. |
| Similarity: | |
Belongs to the DNA polymerase type-A family. {ECO:0000256|ARBA:ARBA00007705, ECO:0000256|RuleBase:RU004460}. |
Annotations taken from UniProtKB at the EBI.