UniProt functional annotation for P01263

UniProt code: P01263.

Organism: Oncorhynchus keta (Chum salmon) (Salmo keta).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus.
 
Function: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
 
Subcellular location: Secreted.
Pharmaceutical: Available under the names Calcimar (Rhone-Poulenc Rorer), Miacalcin (Novartis) or Forcaltonin (Unigene). Used for the treatment of Paget's disease and hypercalcemia in malignancy.
Similarity: Belongs to the calcitonin family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.