UniProt functional annotation for O80337



	UniProt functional annotation for O80337

UniProt code: O80337.

Organism: Arabidopsis thaliana (Mouse-ear cress).

Taxonomy: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.

Function: Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11950980, ECO:0000269|PubMed:9756931}.

Subcellular location: Nucleus {ECO:0000305}.

Tissue specificity: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269|PubMed:11950980}.

Induction: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1. Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2), whereas induction by wounding does not need EIN2. Induction by salicylic acid (SA) seems to be independent of PAD4 and NPR1. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269|PubMed:10715325, ECO:0000269|PubMed:11950980}.

Domain: The AP2/ERF domain binds specifically to the 5'-GCCGCC-3' motif. The affinity of this binding is higher if the seventh amino-acid of this domain is basic (By similarity). {ECO:0000250}.

Similarity: Belongs to the AP2/ERF transcription factor family. ERF subfamily. {ECO:0000305}.

Sequence caution: Sequence=BAA32418.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAB45963.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=CAB78753.1; Type=Frameshift; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.


Organism:		Arabidopsis thaliana (Mouse-ear cress).
Taxonomy:		Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.



Function:		Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:9756931}.


Subcellular location:		Nucleus {ECO:0000305}.
Tissue specificity:		Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269\|PubMed:11950980}.
Induction:		Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Also induced by methyl jasmonate (MeJA) independently of JAR1. Ethylene induction is completely dependent on a functional ETHYLENE-INSENSITIVE2 (EIN2), whereas induction by wounding does not need EIN2. Induction by salicylic acid (SA) seems to be independent of PAD4 and NPR1. Transcripts accumulate strongly in cycloheximide-treated plants, a protein synthesis inhibitor. Seems to not be influenced by exogenous abscisic acid (ABA), cold, heat, NaCl or drought stress. {ECO:0000269\|PubMed:10715325, ECO:0000269\|PubMed:11950980}.
Domain:		The AP2/ERF domain binds specifically to the 5'-GCCGCC-3' motif. The affinity of this binding is higher if the seventh amino-acid of this domain is basic (By similarity). {ECO:0000250}.
Similarity:		Belongs to the AP2/ERF transcription factor family. ERF subfamily. {ECO:0000305}.
Sequence caution:		Sequence=BAA32418.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAB45963.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=CAB78753.1; Type=Frameshift; Evidence={ECO:0000305};