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PDBsum entry 2frv

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protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
2frv
Jmol
Contents
Protein chains
(+ 0 more) 261 a.a. *
(+ 0 more) 530 a.a. *
Ligands
SF4 ×12
F3S ×6
FCO-__O ×6
Metals
_NI ×6
_MG ×6
Waters ×1146
* Residue conservation analysis
PDB id:
2frv
Name: Oxidoreductase
Title: Crystal structure of the oxidized form of ni-fe hydrogenase
Structure: Periplasmic hydrogenase. Chain: s, a, c, e, g, i. Synonym: cytochrome-c3 hydrogenase. Periplasmic hydrogenase. Chain: l, b, d, f, h, j. Synonym: cytochrome-c3 hydrogenase. Ec: 1.18.99.1
Source: Desulfovibrio gigas. Organism_taxid: 879. Collection: atcc 19364. Cellular_location: periplasm. Cellular_location: periplasm
Biol. unit: Hetero-Dimer (from PDB file)
Resolution:
2.54Å     R-factor:   0.202     R-free:   0.219
Authors: A.Volbeda,M.Frey,J.C.Fontecilla-Camps
Key ref: A.Volbeda et al. (1996). Structure of the [nife] hydrogenase active site: evidence for biologically uncommon fe ligands. J am chem soc, 118, 12989.
Date:
10-Jun-97     Release date:   17-Jun-98    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P12943  (PHNS_DESGI) -  Periplasmic [NiFe] hydrogenase small subunit
Seq:
Struc:
288 a.a.
261 a.a.*
Protein chains
Pfam   ArchSchema ?
P12944  (PHNL_DESGI) -  Periplasmic [NiFe] hydrogenase large subunit
Seq:
Struc:
 
Seq:
Struc:
551 a.a.
531 a.a.*
Key:    PfamA domain  PfamB domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 6 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains S, L, A, B, C, D, E, F, G, H, I, J: E.C.1.12.2.1  - Cytochrome-c3 hydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3
      Cofactor: Iron-sulfur; Nickel
Iron-sulfur
Nickel
Molecule diagrams generated from .mol files obtained from the KEGG ftp site
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     periplasmic space   2 terms 
  Biological process     oxidation-reduction process   1 term 
  Biochemical function     oxidoreductase activity     8 terms