PDBsum entry 2f5y

Signaling protein

PDB id: 2f5y

Contents

Protein chains

82 a.a. *

Ligands

SO4 ×2

Waters ×42

* Residue conservation analysis

PDB id:

2f5y

Name:

Signaling protein

Title:

Crystal structure of the pdz domain from human rgs-3

Structure:

Regulator of g-protein signalling 3 isoform 1. Chain: a, b. Fragment: pdz domain (residues 15-103). Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Strain: bl21 (de3). Gene: rgs3. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.39Å R-factor: 0.217 R-free: 0.264

Authors:

E.Ugochukwu,G.Berridge,C.Johansson,C.Smee,P.Savitsky,N.Burgess, S.Colebrook,X.Yang,J.Elkins,D.Doyle,A.Turnbull,E.Papagrigoriou, J.Debreczeni,G.Bunkoczi,F.Gorrec,F.Von Delft,C.Arrowsmith, M.Sundstrom,J.Weigelt,A.Edwards,Structural Genomics Consortium (Sgc)

Key ref:

E.Ugochukwu et al. Crystal structure of the pdz domain from human rgs-3. To be published, .

Date:

28-Nov-05 Release date: 13-Dec-05

Protein chains

P49796  (RGS3_HUMAN) -  Regulator of G-protein signaling 3 from Homo sapiens

Seq: 1198 a.a.

Struc: 82 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)