UniProt functional annotation for Q9Y3R4

UniProt code: Q9Y3R4.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins, oligosaccharides and gangliosides. {ECO:0000269|PubMed:14613940, ECO:0000269|PubMed:22228546}.
 
Catalytic activity: Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. {ECO:0000269|PubMed:14613940, ECO:0000269|PubMed:22228546}.
Subcellular location: Cytoplasm {ECO:0000250}.
Tissue specificity: Expressed in skeletal muscle, fetal liver and embryonic carcinoma cell line NT2-D1. {ECO:0000269|PubMed:10191093}.
Similarity: Belongs to the glycosyl hydrolase 33 family. {ECO:0000305}.
Similarity: Contains 2 BNR repeats. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.