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PDBsum entry 2f25

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Top Page protein ligands Protein-protein interface(s) links
Protein chain A    -    representing identical chain: B PDB id
2f25
Protein chain A highlighted
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Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
5 sheets
17 beta hairpins
17 beta bulges
25 strands
7 helices
1 helix-helix interac
30 beta turns
6 gamma turns
Catalytic residues
D46-E218-Y334
Variants
Ser11Arg
Ala145Thr
Arg41Gln
Arg182Gln
Arg123Gln
Val175Met
Ala328Thr
  
Chain & (373 residues)

UniProt code: Q9Y3R4 (NEUR2_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (1 domain) :
Domain Links CATH no.   Class Architecture
1 2.120.10.10 = Mainly Beta 6 Propellor

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand
PDB SITE records:   
 AC1  AC2  AC3  AC4  AC5
 AC6


FASTA
file
Domain 1
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
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