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PDBsum entry 2eqy
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DNA binding protein
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PDB id
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2eqy
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Contents |
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* Residue conservation analysis
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PDB id:
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DNA binding protein
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Title:
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Solution structure of the arid domain of jarid1b protein
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Structure:
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Jumonji, at rich interactive domain 1b. Chain: a. Fragment: arid domain. Synonym: rbp2 like. Engineered: yes
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Source:
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Mus musculus. House mouse. Organism_taxid: 10090. Gene: jarid1b. Other_details: cell-free protein synthesis
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NMR struc:
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20 models
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Authors:
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W.Tanabe,S.Suzuki,Y.Muto,M.Inoue,T.Kigawa,T.Terada,M.Shirouzu, S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)
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Key ref:
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W.Tanabe
et al.
Solution structure of the arid domain of jarid1b protein.
To be published,
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Date:
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30-Mar-07
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Release date:
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02-Oct-07
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PROCHECK
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Headers
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References
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Q80Y84
(KDM5B_MOUSE) -
Lysine-specific demethylase 5B from Mus musculus
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Seq:
Struc:
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1544 a.a.
122 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 7 residue positions (black
crosses)
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Enzyme class:
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E.C.1.14.11.67
- [histone H3]-trimethyl-L-lysine(4) demethylase.
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Reaction:
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N6,N6,N6-trimethyl-L-lysyl4-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl4-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2
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N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3]
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+
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3
×
2-oxoglutarate
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+
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3
×
O2
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=
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L-lysyl(4)-[histone H3]
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+
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3
×
formaldehyde
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+
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3
×
succinate
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+
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3
×
CO2
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
