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UniProt functional annotation for P50623 | ||
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| UniProt code: P50623. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2). {ECO:0000269|PubMed:11572779, ECO:0000269|PubMed:9341106}. |
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| Pathway: | |
Protein modification; protein sumoylation. |
| Subunit: | |
Interacts with SIZ1. {ECO:0000269|PubMed:11572779, ECO:0000269|PubMed:11587849}. |
| Subcellular location: | |
Nucleus {ECO:0000269|PubMed:14562095}. |
| Miscellaneous: | |
Present with 2600 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the ubiquitin-conjugating enzyme family. {ECO:0000255|PROSITE-ProRule:PRU00388}. |
Annotations taken from UniProtKB at the EBI.