PDBsum entry 2egm

Transcription/metal binding protein

PDB id: 2egm

Contents

Protein chain

57 a.a. *

Metals

_ZN ×2

* Residue conservation analysis

PDB id:

2egm

Name:

Transcription/metal binding protein

Title:

Solution structure of the zf-b_box domain from human tripartite motif protein 41

Structure:

Tripartite motif-containing protein 41. Chain: a. Fragment: zf-b_box domain. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: trim41. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

K.Inoue,T.Nagashima,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

K.Inoue et al. Solution structure of the zf-B_box domain from human tripartite motif protein 41. To be published, .

Date:

01-Mar-07 Release date: 04-Sep-07

Protein chain

Q8WV44  (TRI41_HUMAN) -  E3 ubiquitin-protein ligase TRIM41 from Homo sapiens

Seq: 630 a.a.

Struc: 57 a.a.*

* PDB and UniProt seqs differ at 7 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.
• Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine