UniProt functional annotation for Q8R4T5

UniProt code: Q8R4T5.

Organism: Rattus norvegicus (Rat).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus.
 
Function: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. {ECO:0000269|PubMed:11850456}.
 
Subunit: Heteromer. Composed of TAMALIN, CYTH2 and at least one GRM1. Also interacts with CYTH3, GRM2, GRM3 and GRM5. {ECO:0000250|UniProtKB:Q9JJA9, ECO:0000269|PubMed:11850456}.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:11850456}. Cell membrane {ECO:0000269|PubMed:11850456}; Peripheral membrane protein {ECO:0000269|PubMed:11850456}; Cytoplasmic side {ECO:0000269|PubMed:11850456}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:11850456}.
Tissue specificity: Expressed in brain. {ECO:0000269|PubMed:11850456}.

Annotations taken from UniProtKB at the EBI.