PDBsum entry 2ecj

Metal binding protein

PDB id: 2ecj

Contents

Protein chain

58 a.a. *

Metals

_ZN ×2

* Residue conservation analysis

PDB id:

2ecj

Name:

Metal binding protein

Title:

Solution structure of the ring domain of the human tripartite motif- containing protein 39

Structure:

Tripartite motif-containing protein 39. Chain: a. Fragment: ring domain. Synonym: ring finger protein 23, testis-abundant finger protein. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: trim39. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

K.Miyamoto,M.Sato,S.Koshiba,S.Watanabe,T.Harada,T.Kigawa,S.Yokoyama, Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

K.Miyamoto et al. Solution structure of the ring domain of the human tripartite motif-Containing protein 39. To be published, .

Date:

13-Feb-07 Release date: 14-Aug-07

Protein chain

Q9HCM9  (TRI39_HUMAN) -  E3 ubiquitin-protein ligase TRIM39 from Homo sapiens

Seq: 518 a.a.

Struc: 58 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.
• Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine