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UniProt functional annotation for Q13887 | ||
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| UniProt code: Q13887. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Transcription factor that binds to GC box promoter elements. Activates the transcription of these genes. |
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| Subunit: | |
Interacts with WWP1. Interacts with ANP32B; this interaction induces promoter region-specific histone incorporation and inhibition of histone acetylation by ANP32B. {ECO:0000269|PubMed:15735697, ECO:0000269|PubMed:18039846}. |
| Subcellular location: | |
Nucleus {ECO:0000269|PubMed:15735697}. |
| Tissue specificity: | |
Expressed only in testis and placenta. |
| Domain: | |
The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. {ECO:0000269|PubMed:31375868}. |
| Ptm: | |
Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. {ECO:0000269|PubMed:15735697}. |
| Similarity: | |
Belongs to the krueppel C2H2-type zinc-finger protein family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.