PDBsum entry 2ea6

Transcription

PDB id: 2ea6

Contents

Protein chain

69 a.a. *

Metals

_ZN ×2

* Residue conservation analysis

PDB id:

2ea6

Name:

Transcription

Title:

Solution structure of the ring domain of the human ring finger protein 4

Structure:

Ring finger protein 4. Chain: a. Fragment: ring domain. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf4. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

K.Miyamoto,M.Yoneyama,T.Tomizawa,S.Koshiba,S.Watanabe,T.Harada, T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

K.Miyamoto et al. Solution structure of the ring domain of the human ring finger protein 4. To be published, .

Date:

30-Jan-07 Release date: 31-Jul-07

Protein chain

P78317  (RNF4_HUMAN) -  E3 ubiquitin-protein ligase RNF4 from Homo sapiens

Seq: 190 a.a.

Struc: 69 a.a.*

* PDB and UniProt seqs differ at 7 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.
• Reaction: S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine