PDBsum entry 2e8n

Transferase, signaling protein

PDB id: 2e8n

Contents

Protein chain

88 a.a. *

* Residue conservation analysis

PDB id:

2e8n

Name:

Transferase, signaling protein

Title:

Solution structure of thE C-terminal sam-domain of ephaa2: ephrin type-a receptor 2 precursor (ec 2.7.10.1)

Structure:

Ephrin type-a receptor 2. Chain: a. Fragment: sam domain. Synonym: tyrosine-protein kinase receptor eck, epithelial cell kinase. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: epha2. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

A.K.Goroncy,M.Sato,S.Koshiba,M.Inoue,T.Kigawa,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

A.K.Goroncy et al. Solution structure of the c-Terminal sam-Domain of ephaa2: ephrin type-A receptor 2 precursor (ec 2.7.10.1). To be published, .

Date:

22-Jan-07 Release date: 29-Jan-08

Protein chain

P29317  (EPHA2_HUMAN) -  Ephrin type-A receptor 2 from Homo sapiens

Seq: 976 a.a.

Struc: 88 a.a.*

* PDB and UniProt seqs differ at 6 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.1 - receptor protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site