PDBsum entry 2e5k

Protein binding

PDB id: 2e5k

Contents

Protein chain

94 a.a. *

* Residue conservation analysis

PDB id:

2e5k

Name:

Protein binding

Title:

Solution structure of sh3 domain in suppressor of t-cell receptor signaling 1

Structure:

Suppressor of t-cell receptor signaling 1. Chain: a. Fragment: sh3 domain. Synonym: sts-1, cbl-interacting protein p70. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: sts1. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

S.Sukegawa,K.Tsuda,Y.Muto,M.Inoue,T.Kigawa,T.Terada,M.Shirouzu, S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

S.Sukegawa et al. Solution structure of sh3 domain in suppressor of t-Cell receptor signaling 1. To be published, .

Date:

21-Dec-06 Release date: 26-Jun-07

Protein chain

Q8TF42  (UBS3B_HUMAN) -  Ubiquitin-associated and SH3 domain-containing protein B from Homo sapiens

Seq: 649 a.a.

Struc: 94 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.1.3.48 - protein-tyrosine-phosphatase.
• Reaction: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site