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PDBsum entry 2e40

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Hydrolase PDB id
2e40
Jmol
Contents
Protein chains
459 a.a.
Ligands
LGC ×2
Waters ×921

References listed in PDB file
Key reference
Title Crystal structure of intracellular family 1 beta-Glucosidase bgl1a from the basidiomycete phanerochaete chrysosporium.
Authors Y.Nijikken, T.Tsukada, K.Igarashi, M.Samejima, T.Wakagi, H.Shoun, S.Fushinobu.
Ref. FEBS Lett, 2007, 581, 1514-1520. [DOI no: 10.1016/j.febslet.2007.03.009]
PubMed id 17376440
Abstract
The white-rot fungus Phanerochaete chrysosporium has two intracellular beta-glucosidases (BGL1A and BGL1B) belonging to glycoside hydrolase (GH) family 1. BGL1B effectively hydrolyzes cellobiose and cellobionolactone, but BGL1A does not. We have determined the crystal structure of BGL1A in substrate-free and gluconolactone complexed forms. The overall structure and the characteristic of subsite -1 (glycone site) were similar to those of other known GH1 enzymes. The loop regions covering on the (beta/alpha)(8) barrel was significantly deviated, and they form a unique subsite +1 (aglycone site) of BGL1A.
Secondary reference #1
Title Molecular cloning and characterization of two intracellular beta-Glucosidases belonging to glycoside hydrolase family 1 from the basidiomycete phanerochaete chrysosporium.
Authors T.Tsukada, K.Igarashi, M.Yoshida, M.Samejima.
Ref. Appl Microbiol Biotechnol, 2006, 73, 807-814. [DOI no: 10.1007/s00253-006-0526-z]
PubMed id 16896601
Abstract
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